Must know ‘New Drugs’ for AIIMS-PG
Jun 5, 2020
Pharmacology expert has come up with a list of important 'New Drugs'. This list has been compiled keeping in mind the upcoming AIIMS-PG exam.
After going through this blog, you'll be well versed to answer any question related to this topic in the exam.
IMPORTANT DRUGS FOR AIIMS-PG
The table includes the name of the drug, mechanism, route, and indication.
| Drug | Mechanism | Route | Indication |
| Andexanet alpha | Bind to Factor Xa inhibitors | Intravenous | To reverse overdose of rivaroxaban and apixaban |
| Brexanolone | GABA-A modulator | Intravenous | Post partum depression |
| Baloxavirmarboxil | Inhibit viral replication by inhibiting Cap-dependent endonuclease activity of viral polymerase | Oral | Single dose treatment of Acute uncomplicated influenza |
| Elagolix | GnRH antagonist | Oral | Pain associated with endometriosis |
| Esketamine | Non-competitive NMDA antagonist | Intranasal | Treatment resistant depression |
| Ibalizumab | MAb against CD4 | Intravenous | HIV |
| Pretomanid | Inhibit mycolic acid synthesis | Oral | For XDR and MDR TB (in combination with bedaquiline and linezolid) |
| Pitolisant | H3 antagonist/inverse agonist | Oral | Narcolepsy |
| Tenapanor | Sodium hydrogen exchanger-3 (NHE-3) inhibitor | Oral | IBS with constipation |
| Tafenoquine | Free radical mediated killing of hypnozoites | Oral | Single dose radical cure of P. vivax malaria |
| Lemborexant | Dual Orexin Antagonist (DORA)- binds to both the orexin receptors OX1R and OX2R | Oral | Insomnia |
| Remdesivir | Remdesivir triphosphate inhibits viral RNA dependent RNA polymerase | Intravenous | Coronavirus disease 2019(COVID-19) |
| Ubrogepant | CGRP receptor antagonist | Oral | Acute treatment of migraine with or without aura |
| Rimegepant | CGRP receptor antagonist | Oral | Acute treatment of migraine with or without aura |
| Lasmiditan | 5HT1F agonist | Oral | Acute treatment of migraine with or without aura |
| Erenumab | Monoclonal antibody against CGRP receptor | SC | Migraine prophylaxis |
| Galcanezumab | Monoclonal antibody against CGRP receptor | SC | Migraine prophylaxis |
| Fremanezumab | Binds to CGRP ligand blocking its binding to CGRP receptor. | SC | Migraine prophylaxis |
| Eptinezumab | Binds to CGRP ligand blocking its binding to CGRP receptor. | Intravenous | Migraine prophylaxis |
| Romosozumab | MAB against sclerostin | SC | Osteoporosis in postmenopausal women at high risk of fracture |
Good Luck!
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Srishti Sehgal
A Content Creator with over five years of experience, Srishti is an expert at creating content related to several genres. She aims to make a difference through what she writes.
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